Research
My current research is about studying the in-vivo brain cellular activity affected by drugs using different imaging techniques. Specifically, the calcium change and hemodynamic responses can be analyzed by the multimodal imaging platform; the density, blood flow velocity, and diameter changes in vessels can be quantified by optical coherence tomography (OCT) images.
Besides optical brain imaging, my future research will also include optimizing current OCT systems.
Research interests: optical brain imaging; optical coherence tomography; biophotonics
A schematic of spectral-domain μOCT system for simultaneous 3D μODT and μOCA imaging. CM: collimator, D: dispersion compensator; FPC: fiber polarization controller, L1, L2, L3: achromatic lenses, G: servo mirrors. BS: beam splitter.
(J. You, C. Du, N. Volkow, and Y. Pan, "Optical coherence Doppler tomography for quantitative cerebral blood flow imaging," Biomed. Opt. Express 5, 3217-3230 (2014).)